Thrift Stores in Seneca, SC

We list 6 thrift, second-hand, consignment and donation stores in Seneca, South Carolina, in ZIP code 29678. Each entry links to its Google Maps page for directions, photos and current hours. Store listings from Google Maps data, March 2026. Call ahead, hours change.

Chains in this city: Goodwill (1), Uptown Cheapskate (1). The rest are independent, charity-run or locally owned shops.

All 6 stores in Seneca

• Boys Camp Thrift Store - 714 W North 1st St, Seneca, SC 29678 Open in Google Maps
• Dream Center Resale Store Seneca - 11011 N Radio Station Rd, Seneca, SC 29678 Open in Google Maps
• Goodwill - 1616 Sandifer Blvd, Seneca, SC 29678 Open in Google Maps
• Ripple Resale - 203 Oconee Square Dr, Seneca, SC 29678 Open in Google Maps
• Uptown Cheapskate Clemson - 13180 Clemson Blvd, Seneca, SC 29678 Open in Google Maps
• Wilderness Way Girls Camp Thrift Store - 304 W North 1st St, Seneca, SC 29678 Open in Google Maps

Store listings from Google Maps data, March 2026. Call ahead, hours change. Looking somewhere else? Search by ZIP code, city or distance.

Thrift shopping in Seneca

For chains, store types and buying tips across the state, read the South Carolina thrift store guide.

Other South Carolina cities with store listings

• Easley (6 stores)
• Greenville (11 stores)
• Greenwood (5 stores)
• Spartanburg (7 stores)
• Aiken (8 stores)
• Lexington (9 stores)