Thrift Stores in Cape Girardeau, MO

We list 10 thrift, second-hand, consignment and donation stores in Cape Girardeau, Missouri, in ZIP codes 63701, 63703. Each entry links to its Google Maps page for directions, photos and current hours. Store listings from Google Maps data, March 2026. Call ahead, hours change.

Chains in this city: Plato's Closet (1), Goodwill (1), Habitat ReStore (1), Once Upon a Child (1). The rest are independent, charity-run or locally owned shops.

All 10 stores in Cape Girardeau

• A-1 Resale Consignment Center - 429 Broadway St, Cape Girardeau, MO 63701 Open in Google Maps
• Aesthete Luxury Resale - 108 Main St, Cape Girardeau, MO 63701 Open in Google Maps
• Plato's Closet - 257 N Kingshighway St, Cape Girardeau, MO 63701 Open in Google Maps
• Safe House Thrift Shop - Cape Girardeau, MO 63701 Open in Google Maps
• Sammy's Window Children's Resale Market - 118 Main St, Cape Girardeau, MO 63701 Open in Google Maps
• Teen Challenge Thrift Store - 61 Clark St, Cape Girardeau, MO 63701 Open in Google Maps
• Goodwill Store and Donation Center - 250 S Silver Springs Rd, Cape Girardeau, MO 63703 Open in Google Maps
• Habitat For Humanity ReStore - 501 S Kingshighway, Cape Girardeau, MO 63703 Open in Google Maps
• Once Upon A Child - Cape Girardeau, MO - 760 S Kingshighway, Cape Girardeau, MO 63703 Open in Google Maps
• Vintage Stock - 3049 William St Suite 225, Cape Girardeau, MO 63703 Open in Google Maps

Store listings from Google Maps data, March 2026. Call ahead, hours change. Looking somewhere else? Search by ZIP code, city or distance.

Thrift shopping in Cape Girardeau

For chains, store types and buying tips across the state, read the Missouri thrift store guide.

Other Missouri cities with store listings

• Poplar Bluff (9 stores)
• Arnold (7 stores)
• St. Louis (21 stores)
• St. Peters (6 stores)
• Washington (7 stores)
• Rolla (7 stores)